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SAFRON is the International Atomic Energy Association (IAEA) member state safety in radiation oncology incident learning system. The purpose of the incident learning system is to share information on near misses (or near events) and events that reach the patient in radiotherapy procedures. Radiotherapy is considered a safe medical procedure, but because of its complexity and technological sophistication, errors do occur. By participating in an incident learning system, a radiotherapy facility can find ways to improve the safety systems to assure that patients are not harmed. The system is free, anonymous, and nonpunitive. To participate, the radiotherapy facility needs to register and then be approved by IAEA. Anyone can review the events in the system by registering with the IAEA NUCLEUS system. The updates are provided to share learning opportunities and provide the radiotherapy community with information on ways to strengthen patient safety systems. The development and use of SAFRON is to support member states' efforts to assure the beneficial use of radiation and prevent significant radiation related errors.